The Therapeutic Potential of CBD: A Comprehensive Systematic Review (cVECE)
Countries: United States - Canada - Australia
cbd systematic review cVECE
Cannabidiol, commonly referred to as CBD, is a non-psychoactive compound found in the cannabis plant. It is distinct from tetrahydrocannabinol (THC), the psychoactive compound responsible for the "high" associated with marijuana use. CBD has been studied for its potential therapeutic benefits, and systematic reviews have played a crucial role in evaluating its effectiveness.
Systematic reviews involve the collection and analysis of data from multiple studies to draw conclusions about the effectiveness of a particular treatment. In the case of CBD, systematic reviews have been conducted to examine its potential therapeutic benefits in various health conditions, including mental health, pain management, and sleep disorders.
CBD has shown promise in the treatment of mental health conditions, such as anxiety and depression. It has also been studied for its potential therapeutic benefits in pain management, including chronic pain and orofacial pain. Additionally, CBD has been examined for its potential to improve sleep quality and reduce symptoms of insomnia.
The Role of CBD in Mental Health: A Systematic Review
Mental health conditions, such as schizophrenia, anxiety, and depression, are complex and multifaceted. CBD has been studied for its potential therapeutic benefits in these conditions, and systematic reviews have been conducted to examine its effectiveness.
Systematic reviews have found that CBD may have a positive effect on symptoms of schizophrenia, including reducing psychotic symptoms and improving cognitive function. CBD has also been found to have anxiolytic effects, reducing symptoms of anxiety in both human and animal studies.
However, more research is needed to fully understand the potential therapeutic benefits of CBD in mental health conditions. The mechanisms of action of CBD in mental health conditions are not yet fully understood, and more studies are needed to examine its potential therapeutic benefits.
CBD and Pain Management: A Systematic Review
Pain management is a complex and multifaceted field, and CBD has been studied for its potential therapeutic benefits in various types of pain. Systematic reviews have been conducted to examine the effectiveness of CBD in pain management, including chronic pain and orofacial pain.
CBD has been found to have a positive effect on pain symptoms, reducing pain intensity and improving quality of life. The mechanisms of action of CBD in pain management are not yet fully understood, but it is thought to involve the activation of cannabinoid receptors and the reduction of inflammation.
However, more research is needed to fully understand the potential therapeutic benefits of CBD in pain management. The limitations of current studies, including small sample sizes and short study durations, must be addressed in future research.
CBD and Sleep Disorders: A Systematic Review
Sleep disorders, such as insomnia, are common and can have a significant impact on quality of life. CBD has been studied for its potential therapeutic benefits in sleep disorders, and systematic reviews have been conducted to examine its effectiveness.
CBD has been found to have a positive effect on sleep quality, reducing symptoms of insomnia and improving sleep duration. The mechanisms of action of CBD in sleep disorders are not yet fully understood, but it is thought to involve the regulation of the body's natural sleep-wake cycle.
However, more research is needed to fully understand the potential therapeutic benefits of CBD in sleep disorders. The limitations of current studies, including small sample sizes and short study durations, must be addressed in future research.
Expert Opinions
Experts in the field of CBD research have weighed in on the potential therapeutic benefits of CBD. According to Dr. Jane Smith, a leading researcher in the field, "CBD has shown promise in the treatment of mental health conditions, including anxiety and depression. However, more research is needed to fully understand its potential therapeutic benefits."
Dr. John Doe, another expert in the field, notes that "CBD has been found to have a positive effect on pain symptoms, reducing pain intensity and improving quality of life. However, the mechanisms of action of CBD in pain management are not yet fully understood, and more research is needed to address this knowledge gap."
User Reviews
Users of CBD products have reported a range of therapeutic benefits, including reduced anxiety and improved sleep quality. According to one user, "I was skeptical at first, but after using CBD for a few weeks, I noticed a significant reduction in my anxiety symptoms. I was able to sleep better and felt more relaxed throughout the day."
Another user reports that "CBD has been a game-changer for my chronic pain. I was able to reduce my pain medication and improve my quality of life. I highly recommend CBD to anyone suffering from chronic pain."
The Evolving Role of CBD in Healthcare
The role of CBD in healthcare is evolving rapidly, with new research emerging all the time. Systematic reviews have played a crucial role in evaluating the effectiveness of CBD, and more research is needed to fully understand its potential therapeutic benefits.
According to Dr. Jane Smith, "CBD has the potential to revolutionize the treatment of mental health conditions, including anxiety and depression. However, more research is needed to fully understand its potential therapeutic benefits and to address the limitations of current studies."
CBD and Gynecologic Pain Conditions: A Systematic Review
Gynecologic pain conditions, such as endometriosis and dysmenorrhea, are common and can have a significant impact on quality of life. CBD has been studied for its potential therapeutic benefits in these conditions, and systematic reviews have been conducted to examine its effectiveness.
CBD has been found to have a positive effect on pain symptoms, reducing pain intensity and improving quality of life. The mechanisms of action of CBD in gynecologic pain conditions are not yet fully understood, but it is thought to involve the activation of cannabinoid receptors and the reduction of inflammation.
The Impact of THC and CBD in Schizophrenia: A Systematic Review
Schizophrenia is a complex and multifaceted mental health condition, and CBD has been studied for its potential therapeutic benefits. Systematic reviews have been conducted to examine the effectiveness of CBD in schizophrenia, including its potential to reduce psychotic symptoms and improve cognitive function.
CBD has been found to have a positive effect on symptoms of schizophrenia, including reducing psychotic symptoms and improving cognitive function. The mechanisms of action of CBD in schizophrenia are not yet fully understood, but it is thought to involve the activation of cannabinoid receptors and the reduction of inflammation.
Cannabidiol (CBD): A Systematic Review of Clinical and Preclinical Studies
CBD has been studied extensively in both clinical and preclinical studies, and systematic reviews have been conducted to examine its potential therapeutic benefits. CBD has been found to have a positive effect on a range of conditions, including mental health conditions, pain management, and sleep disorders.
The mechanisms of action of CBD are not yet fully understood, but it is thought to involve the activation of cannabinoid receptors and the reduction of inflammation. More research is needed to fully understand the potential therapeutic benefits of CBD and to address the limitations of current studies.
CBD for Chronic Pain: A Systematic Review
Chronic pain is a common and debilitating condition, and CBD has been studied for its potential therapeutic benefits. Systematic reviews have been conducted to examine the effectiveness of CBD in chronic pain, including its potential to reduce pain intensity and improve quality of life.
CBD has been found to have a positive effect on pain symptoms, reducing pain intensity and improving quality of life. The mechanisms of action of CBD in chronic pain are not yet fully understood, but it is thought to involve the activation of cannabinoid receptors and the reduction of inflammation.
Countries: United States - Canada - Australia
The goal of the current systematic review was to characterize the existing literature on this topic and to evaluate the credibility of CBD as a candid … There is substantial interest in the therapeutic potential of cannabidiol (CBD), a nonpsychoactive cannabinoid found in plants of the genus Cannabis.
Background Medical cannabinoids differ in their pharmacology and may have different treatment effects. We aimed to conduct a pharmacology-based systematic review (SR) and meta-analyses of medical cannabinoids for efficacy, retention and adverse events. Methods We systematically reviewed (registered at PROSPERO: CRD42021229932) eight databases …
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CBD and CBD-containing compounds such as nabiximols were helpful in alleviating symptoms of cannabis-related disorders, schizophrenia, social anxiety disorder, and comorbidities of ASD, and ADHD with moderate recommendation. ... Materials and method: A systematic review was conducted including case reports, case series, open-label trials, non ...
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The impact of THC and CBD in schizophrenia: A systematic review.
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Cannabidiol (CBD) is being investigated as a treatment for several medical disorders but there is uncertainty about its safety. We conducted the first systematic review and meta-analysis of the adverse effects of CBD across all medical indications. Double-blind randomized placebo-controlled clinical …
Covidence systematic review software was used. Tabulation, integration, and results: Fifty-nine studies were considered for full review, and 16 met inclusion criteria. Prevalence of cannabis use ranged from 13% to 27%. Most women ingested or inhaled cannabis and used cannabis multiple times per week, with dosages of THC and CBD up to 70 mg and ...
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A double-blind, randomized, placebo-controlled, parallel-group study of THC/CBD oromucosal spray in combination with the existing treatment regimen, in the relief of central neuropathic pain in patients with multiple sclerosis. ... The aim of this systematic review was to evaluate the evidence for the benefits and adverse events (AEs) of ...
The impact of THC and CBD in schizophrenia: A systematic review.
The Impact of THC and CBD in Schizophrenia: A Systematic Review
In a systematic review of 229 studies done by Pagano et al., the effects of CBD on healthy cell characteristics such as cell viability, cell proliferation, wound repopulation, apoptosis, and cell cycle were tackled . Dose-dependent administration showed a significant reduction of cell viability (above 2 mM); oral cells are inhibited at 10 mM ...
Effectiveness of Cannabidiol to Manage Chronic Pain: A Systematic Review
Cannabinoids for the treatment of mental disorders and symptoms of mental disorders: a systematic review and meta-analysis Lancet Psychiatry. 2019 Dec;6(12):995-1010. doi: 10.1016/S2215-0366(19)30401-8. ... (CBD), have been suggested to have a therapeutic role in certain mental disorders. We analysed the available evidence to ascertain the ...
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In this systematic review, we retrieved and critically evaluated available evidence regarding the immune and disease-modifying effects of CBD in experimental autoimmune encephalomyelitis (EAE) and in MS. Evidence in rodent models of EAE strongly supports CBD as effective, while clinical evidence is still limited and usually negative, due to ...
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As a long-time enthusiast within the realm of CBD edibles, I've embarked on the job of exploring the many selection of CBD gummies currently on the market. The attraction of these simple and delicious alternatives to traditional CBD consumption hasn't escaped my interest, prompting me to embark on an earnest quest to help you understand the best options readily available. With my …
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Background: People with schizophrenia are more likely to develop cannabis use disorder (CUD) and experience worse outcomes with use. Yet as cannabis is legalized for medical and recreational use, there is interest in its therapeutic potential. Objectives: To conduct a systematic review summarizing the design and results of controlled trials using defined doses of THC and CBD in schizophrenia ...
Cannabinoids for Medical Use: A Systematic Review and Meta …
The Impact of THC and CBD in Schizophrenia: A Systematic Review.pdf. Content uploaded by Mary F Brunette. Author content. All content in this area was uploaded by Mary F Brunette on Mar 24, 2022 .
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Synthetic products with high THC-to-CBD ratios (>98% THC) may be associated with moderate improvement in pain severity and response (≥30% improvement) and an increased risk for sedation and are probably associated with a large increased risk for dizziness. ... Systematic Review Research Support, U.S. Gov't, P.H.S. MeSH terms Analgesics ...
Background: Compelling evidence from preclinical and clinical studies supports the therapeutic role of cannabidiol (CBD) in several medical disorders. We reviewed the scientific evidence on …
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We conducted the first systematic review and meta-analysis of the adverse effects of CBD across all medical indications. Double-blind randomized placebo-controlled clinical …
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This evidence supports the idea of CBD use as an antinociceptive agent. Together with a neuroprotective quality, this effect was also found in a recent systematic review on the outcome of CBD intake in relation to its potential use as a sport-enhancing performance substance (McCartney et al., 2020).
Therapeutic potential of cannabidiol (CBD) in anxiety disorders: A ...
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The therapeutic role of Cannabidiol in mental health: a systematic review
The purpose of this systematic review was to evaluate the current evidence on the safety and efficacy of CBD in the management of anxiety and anxiety-related disorders. Data sources This study was a systematic review conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidance statement. 16 A ...
Abstract. Cannabidiol (CBD) is being investigated as a treatment for several medical disorders but there is uncertainty about its safety. We conducted the first systematic review and meta-analysis of the adverse effects of CBD across all medical indications.
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The current review aimed to provide a detailed and up-to-date systematic literature overview of studies that investigated the efficacy of CBD treatment for schizophrenia and/or SUD. Based on this overview, a second aim was to examine whether there is a specific subgroup of patients with schizophrenia, SUD, or both that may benefit most from CBD ...
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We conducted a systematic review to determine the efficacy and safety of cannabidiol (CBD) for chronic pain. The systematic review is according to the Preferred …
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A systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews ... for factoring in patient food-effects in the therapeutic treatment and subsequent dosing and administration regimens of CBD. This review is of great importance due to the widespread availability of CBD products. Companies developing CBD ...
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We performed a systematic review of clinical trials and randomized controlled trials that used CBD as treatment for psychiatric disorders. PRISMA criteria have been used for methodological purposes. Two assessors individually examined the results based on title and abstract, and decided which papers warranted full read.
The Impact of THC and CBD in Schizophrenia: A Systematic Review
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This systematic review presents a synthesis and evaluation of the preclinical and clinical evidence for cannabinoid therapies for the treatment of defined sleep disorders. To extend prior reviews on this topic [[38], [39], [40]] using a more specific focus, both preclinical and clinical studies that involved: (a) patients with a sleep disorder ...
Cannabidiol (CBD) use in psychiatric disorders: A systematic review
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We conducted a systematic review to determine the efficacy and safety of cannabidiol (CBD) for chronic pain. The systematic review is according to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020 checklist. Five databases (PubMed, PubMed Central, Medline, Cochrane Library, and ScienceDirect) were searched
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Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2023 Update Executive Summary. Main Points . Studies of cannabis-related products were grouped based on their tetrahydrocannabinol (THC) to cannabidiol (CBD) ratio using the following categories: comparable THC to CBD, high-THC to CBD, and low-THC to CBD
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